Any vial in your inventory with the thrown property will work, I think. And maybe the weapon coatings, too. The smoke powder kegs and firewine barrels will work too, if your character is strong enough.

Oh that fight is nasty. I’ve had luck sneaking up to the rafters and starting a surprise round.

… or go full nuclear. Backpack stuffed with explosives, thrown at his feet. Pouches don’t work because the container needs hp in order for it to all explode at once.

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You can change the difficulty setting at any time, except in honour mode.

Which boss?